| Calcitriol treatment is safe and increases frataxin levels in Friedreich Ataxia patients. |
2024 |
Alemany Perna, B.; Tamarit, J.; Cabiscol, E.; Delaspre, F.; Miguela, A.; Huertas Pons, J.M.; Quiroga Varela, A.; Merchan Ruiz, M.; López Domínguez, D.; Ramió i Torrentà, L.; Genís, D.; Ros, J. |
Article d'investigació |
| Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models |
2023 |
Sanz Alcázar,, A.; Britti, E.; Delaspre, F.; Medina Carbonero, M.; Pazos Gil, M.; Tamarit, J.; Ros, J., Cabiscol, E. |
Article d'investigació |
| Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations. |
2022 |
Medina Carbonero, M.; Sanz Alcázar, A.; Britti, E.; Delaspre, F.; Cabiscol, E.; Ros, J.; Tamarit, J. |
Article d'investigació |
| Mitochondrial iron and calcium homeostasis in Friedreich ataxia |
2021 |
Tamarit, J.; Britti, E.; Delaspre, F.; Medina Carbonero, M.; Sanz Alcázar, A.; Cabiscol, E.; Ros, J. |
Article d'investigació |
| Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia. |
2021 |
Britti, E.; Delaspre, F.; Sanz-Alcázar, A.; Medina-Carbonero, M.; Llovera, M.; Purroy, R.; Mincheva-Tasheva, S.; Tamarit, J.; Ros, J. |
Article d'investigació |
| Mitochondrial localization of the yeast forkhead factor Hcm1 |
2020 |
Rodríguez Colman, M.J.; Ros, J.; Cabiscol, E. |
Article d'investigació |
| PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia. |
2020 |
Rodríguez Pascau, L.; Britti, E.; Calap Quintana, P.; Dong, Y.N.; Vergara, C.; Delaspre, F.; Medina Carbonero, M.; Tamarit, J.; Pallardó, F.V.; Gonzalez Cabo, P.; Ros, J.; Lynch, D.R.; Martinell, M.; |
Article d'investigació |
| Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na+/Ca2+ Exchanger, NCLX, and Apoptosis |
2020 |
Britti, E.; Delaspre, F.; Tamarit, J.; Ros, J. |
Article d'investigació |
| Frataxin-deficient cardiomyocytes present an altered thiol-redox state which targets actin and pyruvate dehydrogenase |
2020 |
Purroy, R.; Medina Carbonero, M.; Ros, J.; Tamarit, J. |
Article d'investigació |
| Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death |
2019 |
Britti, E.; Ros, J.; Esteras, N.; Abramov, A.Y. |
Article d'investigació |
| Mitochondrial pore opening and loss of Ca2+ exchanger NCLX levels occur after frataxin depletion |
2018 |
Purroy R; Britti E; Delaspre F; Tamarit J; Ros J. |
Article d'investigació |
| Mitochondrial calcium signaling and neurodegenerative diseases |
2018 |
Elena Britti; Fabien Delaspre; Jordi Tamarit; Joaquim Ros. |
Article d'investigació |
| Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function. |
2018 |
Fernandez-Fernandez S; Bobo-Jimenez V; Requejo-Aguilar R; Gonzalez-Fernandez S; Resch M;Carabias-Carrasco M; Ros J; Almeida A; Bolaños JP. |
Article d'investigació |
| Iron in Friedreich Ataxia: A Central Role in the Pathophysiology or an Epiphenomenon? |
2018 |
Alsina, D.; Purroy, R.; Ros, J.; Tamarit, J. |
Review |
| Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm. |
2018 |
Jiménez-Altayó F; Meirelles T; Crosas-Molist E; Sorolla MA; Del Blanco DG; López-Luque J; Mas-Stachurska A; Siegert AM; Bonorino F; Barberà L; García C; Condom E; Sitges M; Rodríguez-Pascual F; Laurin |
Article d'investigació |
| Nitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast |
2018 |
Alsina D, Ros J, Tamarit J. |
Article d'investigació |
| Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment |
2017 |
Britti E, Delaspre F, Feldman A, Osborne M, Greif H, Tamarit J, Ros J. |
Article d'investigació |
| Protein carbonylation: Principles, Analysis and Biological implications |
2017 |
Ros J. (Ed.) |
Llibre d'investigació |
| Specificity of protein carbonylation and its relevance in aging |
2017 |
Cabiscol E; Tamarit J; Ros J. |
Capítol de llibre d'investigació |
| Protein carbonylation: principles, analysis, and biological implications |
2017 |
Ros J. |
Editor llibre d'investigació |
| Oxidative stress and altered lipid metabolism in Friedreich ataxia |
2016 |
Tamarit J; Obis E; Ros J. |
Article d'investigació |
| Protein carbonylation: proteomics, specificity and relevance to aging |
2014 |
Cabiscol E, Tamarit J, Ros J. |
Review |
| Apoptotic cell death and altered calcium homeostasis caused by frataxin depletion in dorsal root ganglia neurons can be prevented by BH4 domain of Bcl-x(L) protein |
2014 |
Mincheva-Tasheva S, Obis E, Tamarit J, Ros J. |
Article d'investigació |
| Frataxin deficiency in neonatal rat ventricular myocytes targets mitochondria and lipid metabolism |
2014 |
Obis È, Irazusta V, Sanchís D, Ros J, Tamarit J. |
Article d'investigació |
| The FOX transcription factor Hcm1 regulates oxidative metabolism in response to early nutrient limitation in yeast. Role of Snf1 and Tor1/Sch9 kinases |
2013 |
Rodriguez-Colman MJ; Sorolla MA; Vall-llaura N; Tamarit J; Ros J; Cabiscol E |
Article d'investigació |
| Metabolic remodeling in frataxin-deficient yeast is mediated by Cth2 and Adr1 |
2013 |
Moreno-Cermeño A, Alsina D, Cabiscol E, Tamarit J, Ros J. |
Article d'investigació |
| Analysis of oxidative stress-induced protein carbonylation using fluorescent hydrazides. |
2012 |
Tamarit J, de Hoogh A, Obis E, Alsina D, Cabiscol E, Ros J. |
Article d'investigació |
| Protein oxidation in Huntington disease |
2012 |
Sorolla MA, Rodríguez-Colman MJ, Vall-llaura N, Tamarit J, Ros J, Cabiscol E |
Review |
| Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation |
2011 |
Sorolla MA, Nierga C, Rodríguez-Colman MJ, Reverter-Branchat G, Arenas A, Tamarit J, Ros J, Cabiscol E. |
Article d'investigació |
| Frataxin depletion in yeast triggers upregulation of iron transport systems before affecting iron-sulfur enzymes activities |
2010 |
Moreno-Cermeno A, Obis E, Belli G, Cabiscol E, Ros J, Tamarit J. |
Article d'investigació |
| Yeast frataxin mutants display decreased superoxide dismutase activities crucial to promote protein oxidative damage |
2010 |
Irazusta V, Obis E, Moreno-Cermeno A, Cabiscol E, Ros J, Tamarit J. |
Article d'investigació |
| The Forkhead Transcription Factor Hcm1 Promotes Mitochondrial Biogenesis and Stress Resistance in Yeast |
2010 |
Rodriguez-Colman MJ, Reverter-Branchat G, Sorolla MA, Tamarit J, Ros J, Cabiscol E. |
Article d'investigació |
| Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass |
2010 |
Gomez-Pastor R, Perez-Torrado R, Cabiscol E, Ros J, Matallana E. |
Article d'investigació |
| Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism |
2010 |
Sorolla MA, Rodríguez-Colman MJ, Tamarit J, Ortega Z, Lucas JJ, Ferrer I, Ros J, Cabiscol E |
Article d'investigació |
| Proteomic strategies for the analysis of carbonyl groups on proteins |
2010 |
Irazusta V.; Moreno Cermeño A.; Cabiscol E.; Tamarit J.; Ros J. |
Article d'investigació |
| Proteomic and oxidative stress analysis in human brain samples of Huntington disease |
2008 |
Sorolla MA, Reverter-Branchat G, Tamarit J, Ferrer I, Ros J, Cabiscol E |
Article d'investigació |
| Bioquímica II |
2008 |
Ros J |
Publicació electrònica docent |
| Metabolisme i endocrinologia metabòlica |
2008 |
Ros J |
Publicació electrònica docent |
| Major targets of iron-induced protein oxidative damage in frataxin-deficient yeasts are magnesium-binding proteins |
2008 |
Irazusta V, Moreno-cermeño A, Cabiscol E, Ros J, Tamarit J |
Article d'investigació |
| Redox control and oxidative stress in yeast cells |
2008 |
Herrero E, Ros J, Bellí G, Cabiscol E. |
Review |
| Chronological and replicative life-span extension in Saccharomyces cerevisiae by increased dosage of alcohol dehydrogenase 1 |
2007 |
Reverter-Branchat G, Cabiscol E, Tamarit J, Sorolla MA, de la Torre MA, Ros J |
Article d'investigació |
| Glutaredoxins in fungi. |
2006 |
Herrero E, Ros J, Tamarit J, Belli G |
Article d'investigació |
| Manganese is the link between frataxin and iron-sulfur deficiency in the yeast model of Friedreich ataxia |
2006 |
Irazusta V, Cabiscol E, Reverter-Branchat G, Ros J, Tamarit J |
Article d'investigació |
| Colorimetric assay for the quantitation of iron in yeast |
2006 |
Tamarit J, Irazusta V, Moreno-Cermeno A, Ros J |
Article d'investigació |
| Metabolisme i endocrinologia metabòlica |
2006 |
Ros J |
Publicació electrònica docent |
| Bioquímica II |
2006 |
Ros J |
Publicació electrònica docent |
| Oxidative damage to proteins: Structural modifications and consequences in cell function. |
2006 |
Cabiscol E, Ros J |
Capítol de llibre d'investigació |
| Oxidative damage to specific proteins in replicative and chronological-aged Saccharomyces cerevisiae. Common targets and prevention by calorie restriction |
2004 |
Reverter-Blanchat G, Cabiscol E, Tamarit J, Ros J. |
Article d'investigació |
| Novel antioxidant role of alcohol dehydrogenase E from Escherichia coli |
2003 |
Echave P, Tamarit J, Cabiscol E, Ros J. |
Article d'investigació |
| Biochemical characterization of yeast mitochondrial Grx5 monothiol glutaredoxin |
2003 |
Tamarit J, Bellí G, Cabiscol E, Herrero E, Ros J. |
Article d'investigació |
| Grx5 is a mitochondrial glutaredoxin required for the maturation of iron/sulfur enzymes |
2002 |
Rodríguez-Manzaneque MT, Tamarit J, Bellí G, Ros J, Herrero E. |
Article d'investigació |
| Structure-function analysis of yeast Grx5 monothiol glutaredoxin defines essential amino acids for the function of the protein |
2002 |
Bellí G, Polaina J, Tamarit J, de la Torre MA, Rodríguez-Manzaneque MT, Ros J, Herrero E. |
Article d'investigació |
| Mitochondrial Hsp60, resistance to oxidative stress and the labile iron pool are closely connected in Saccharomyces cerevisiae |
2002 |
Cabiscol E, Bellí G, Tamarit J, Echave P, Herrero E, Ros J. |
Article d'investigació |
| DnaK dependence of mutant ethanol oxidoreductases evolved for aerobic function and protective role of the chaperone against protein oxidative damage in Escherichia coli. |
2002 |
Echave P, Esparza-Ceron MA, Cabiscol E, Tamarit J, Ros J, Membrillo-Hernandez J, Lin ECC. |
Article d'investigació |
| Evolution of the AdhE gene product of E. coli from a functional reductase to a dehydrogenase |
2000 |
Membrillo-Hernández J, Echave P, Cabiscol E, Tamarit J, Ros J, Lin ECC. |
Article d'investigació |
| Yeast glutaredoxins and protection against oxidative stress |
2000 |
Herrero E, Ros J. |
Review |
| Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae |
2000 |
Cabiscol E, Piulats E, Echave P, Herrero E, Ros J. |
Article d'investigació |
| Evolution of the adhE gene product of Escherichia coli from a functional reductase to a dehydrogenase: structual and kinetic studies of the mutant proteins |
2000 |
Membrillo-Hernandez J, Echave P, Cabiscol E, Tamarit J, Lin ECC, Ros J. |
Article d'investigació |
| Oxidative stress in Bacteria and protein damage by reactive oxygen species |
2000 |
Cabiscol E, Tamarit J, Ros J. |
Article d'investigació |
| Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae |
1999 |
Rodríguez-Manzaneque MT, Ros J, Cabiscol E, Sorribas A, Herrero E. |
Article d'investigació |
| Identification of the major oxidatively damaged proteins in E. Coli cells exposed to exidative stress |
1998 |
Tamarit J, Cabiscol E, Ros J. |
Article d'investigació |
| Site-directed mutagenesis studies of the metal-binding center of the iron-dependent propanediol oxido-reductase of E. Coli |
1998 |
Obradors N.; Cabiscol E.; Aguilar J.; Ros J. |
Article d'investigació |
| Evolution of an E. Coli protein with increased resistance to oxidative stress |
1998 |
Lu Z, Cabiscol E, Obradors N, Tamarit J, Ros J, Aguilar J, Lin ECC. |
Article d'investigació |
| Differential innactivation of alcohol dehydrogenase isoenzymes in zymomonas mobilis by oxigen |
1997 |
Tamarit J, Cabiscol E, Aguilar J, Ros J. |
Article d'investigació |
| Metal-catalyzed oxidation of fe-dehydrogenases: A consensus target sequence between propanediol oxidoreductase of E. coli and alcohol dehydrogenase II of Z. mobilis |
1994 |
Cabiscol E, Aguilar J, Ros J. |
Article d'investigació |
| Inactivation of propanediol oxidoreductase of E. coli by metal-catalyzed oxidation reaction |
1992 |
Cabiscol E, Hidalgo E, Badia J, Baldomà L, Aguilar J, Ros J. |
Article d'investigació |
| Oxygen regulation of L-1,2-propanediol oxidoreductase activity in E. coli |
1990 |
Cabiscol E.; Hidalgo E.; Badia J.; Baldomà L.; Ros J.; Aguilar J. |
Article d'investigació |
| Propanediol oxidoreductases of E. coli, K. pneumoniae and S. typhimurium. Aspects of interspecies structural and regulatory differentiation |
1985 |
Ros J, Aguilar J. |
Article d'investigació |
| Fermentation mechanism of fucose and rhamnose in S. typhimurium and K. pneumoniae |
1985 |
Badia J, Ros J, Aguilar J. |
Article d'investigació |
| Genetic and structural evidence of the presence of propanediol oxidoreductase isoenzymes in E. coli |
1984 |
Ros J, Aguilar J. |
Article d'investigació |
| Identification of lactaldehyde dehydrogenase and glycoaldehyde dehydrogenase as functions of the same protein in E. coli |
1983 |
Caballero E, Baldomà L, Ros J, Boronat A, Aguilar J. |
Article d'investigació |
| Use of operon fusions to examine the regulation of the L-1,2-propanediol oxidoreductase gene of the fucose system in E. coli K12 |
1983 |
Chen YM, Lin ECC, Ros J, Aguilar J. |
Article d'investigació |
| Regulación de la división celular en Salmonella typhimurium:efecto de la acumulación de RNA y de la densidad celular |
1982 |
Herrero E, Aldea M, Ros J, Monfort J M, Guerrero R |
Capítol de llibre d'investigació |
